matter-lab Mental health technologies for research, assessment, and intervention
I direct the MATTER Lab at the Child Mind Institute in Manhattan, where we build technologies such as wearable devices, phone apps, and voice analysis and informatics tools to help diagnose, assess, monitor and improve mental health. An example wearable device is our wrist-worn position tracker called the “Tingle” that records and remotely monitors compulsive behaviors (such as trichotillomania, excoriation, and nail biting) and can provide an alert when engaging in a such behaviors (by haptic feedback on the wrist). We have created apps to remotely administer therapies for children with anxiety disorders, as well as a general-purpose data collection platform called “Mindlogger” to administer a wide range of assessments, including surveys, drawing and tapping tasks, and audio recordings. We support the Healthy Brain Network, an ongoing study of 10,000 children and adolescents that collects and freely disseminates data from brain imaging, eye tracking, voice, video, biosamples, and a large battery of mental health assessments. Our work therefore combines a patient network, data collection and analysis, intervention platforms and delivery platforms. This combination will enable us to increase access to relevant treatment options, improve mental health assessment and treatment efficacy and support research programs in mental health globally.
mPower Mobile health research: mPower Parkinson study
At Sage Bionetworks, I was the scientific lead on the mPower mobile health research study that tracked symptoms of Parkinson disease in thousands of participants. I helped map symptoms to sensors in the design of the mPower app, a mobile phone application that collects voice, accelerometer, and tapping data. This was one of the first research applications built on top of Apple's new open source ResearchKit platform. I built the mhealthx software pipeline for extracting features from such mobile health data.
Sage_logo Open science challenges
At Sage Bionetworks, in addition to brain imaging and mobile health research projects (see mPower above), I helped coordinate international biomedical contests, such as the Alzheimer''s Disease Big Data Challenge.
(See my 2015 and 2016 Sage Assembly posters and sign!)
mindboggle_logo Mindboggle brain image analysis software
mindboggle.info
I am the lead developer of Mindboggle, Python software for the analysis (feature extraction, labeling, and morphometry) of brain image data. The software has been used to prepare data for an international Alzheimer's challenge, has been funded by three NIH grants, and is under active development.
roygbiv Mindboggle's ROYGBIV brain image viewer
roygbiv.mindboggle.info
As part of the Human Brain Mapping 2015's Hackathon, Anisha Keshavan and I put together a browser-based, interactive brain surface visualization tool. Simple plots of Mindboggle shape measures accompany the anatomically labeled brain regions. This is under active development.
braincolor_logo Mindboggle's BrainCOLOR brain labeling projects
binarybottle.com/braincolor
Early brain labeling project supporting Mindboggle that introduced a labeling protocol, software for generating an optimized brain colormap, and a brain image volume viewer.
elloradaily Ellora Daily Photo
elloradaily.info
I take a photograph of my daughter's face every day (not as consistently now that she's over 14 years old!) and use facial features to coregister the images to create a time-lapse animation of her entire life. This project has been showcased in articles in the L.A. Times and Slate Magazine and has aired on Japan's NHK and Germany's DW-TV.
elloracaves Ellora Cave Temples
elloracaves.org
My wife and I collaborated with Professor Walter Spink of the University of Michigan to create the first comprehensive documentation of the Ellora cave temples of India. I took over 7,000 digital photographs of the Buddhist, Hindu, and Jain cave temples and have constructed an online "walk through" user interface to view the images with respect to the temple ground plans. This work was funded in part by a grant from the Mellon Foundation and several grants from the Indian government.
infovis Information visualization taxonomy and language
infovis.info
I created this searchable database of over 1,000 information visualizations to guide development of a taxonomic classification system for organizing and graphical language for symbolically representing such visualizations.
qovert Quotes over Time
QoverT
Quotes over Time tracked the top-quoted people from Reuters Alertnet News, and presents their quotes on a timeline.
toad Personal websites
KAKlein.com:   my mother's art portfolio
ArnoldKleinGallery.com:   my parents' gallery of fine art
Pupating.org:   my brother's entomology and art
CulturalEntomology.org:   my brother's cultural entomology
KorinthianViolins.com:   my sister's violin shop